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The primary detriment to quality of life associated with CNs derives from tumor disfigurement, while over 90% of patients on currently approved MEK inhibitors additionally experience a conspicuous acneiform rash

Maintaining optimal glutathione levels is crucial for overall health

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These findings align with previous studies that have demonstrated the beneficial effects of VC on enhancing innate immunity in fish, including the activation of lysozyme and complement activities, phagocytic function, and respiratory burst (Dawood and Koshio 2018

Moreover, OsGSTL1 and OsGSTL2 are both constitutively expressed and involved in xenobiotic and oxidative stress tolerance in rice, whereas OsGSTL2 is also specifically up-regulated in roots after herbicide (chlorsulfuron and glyphosate) and hormone treatments (salicylic acid and naphthalene acetic acid) (Hu et al., 2009, 2011a,b)