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Anti-nociceptive mechanisms provide an analgesic effect directly against incision, while anti-inflammatory mechanisms for wound healing can also provide an analgesic effect

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BPC 157 application largely counteracted changes at the microscopic level, including the formation of vacuoles and the loss of axons in the white matter, the formation of edema and the loss of motoneurons in the gray matter, and a decreased number of large myelinated axons in the rat caudal nerve from day 7

This difference explains why stem cell and peptide therapy are increasingly considered a combined strategy