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Mills EA, Ogrodnik MA, Plave A, Mao-Draayer Y (2018) Emerging understanding of the mechanism of action for dimethyl fumarate in the treatment of multiple sclerosis

444 Many studies suggest that high glucose triggers increased mitochondrial fission in retinal capillaries, which induces cell death through the activation of pro-apoptotic genes and other methods, thereby triggering diabetic retinopathy

Several plant foods are also good sources

This makes it a pleiotropic regulator , a molecule that modulates many processes, all of which are important for regeneration and slowing of ageing

Lewis CM, Cler LR, Bu DW, Zochbauer-Muller S, Milchgrub S, Naftalis EZ, Leitch AM, Minna JD, Euhus DM