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A significant problem with these therapies is the increased GSH levels, which is an adaptation of cancer cells to augmented metabolic processes

Vacca et al

They can positively impact enteric diseases and oxidative stress by altering gut microbiota composition and producing short-chain fatty acids (SCFAs) (214)

Broadly, interventions fall into a few categories: dietary modifications and prebiotics, probiotic supplementation, fecal microbiota transplantation, direct microbial metabolite (postbiotic) supplementation, and emerging approaches like phage or small-molecule therapies targeting microbial pathways