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The diagnosis of fish allergy is established by combining the medical history with results from serological specific IgE-antibody determination and results from skin reactivity tests using authentic fish or fish extracts (Figure 1)

NE, along with 5HT, ACh, histamine, and orexin, is a critical regulator of the sleep-wake cycle and of levels of arousal

Summary Keywords bone metabolism, complement system, innate immunity, macrophages, osteoporosis, targeted therapy, trained immunity Citation Kou W, Lu X, Zhang Z, Liu K, Liu Z, Jiang B, Wang H, Li J, Lu H, Guo C, Cao L and Zhang X (2026) Targeting innate immunity to modulate bone metabolism: a novel strategy for osteoporosis treatment

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doi: 10.1016/j.molcel.2022.03.022, 22