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Ribas V, Drew BG, Zhou Z et al (2016) Skeletal muscle action of estrogen receptor is critical for the maintenance of mitochondrial function and metabolic homeostasis in females

It makes B12 a less likely cause and points you toward the next one, often thyroid function, which causes the same kind of washed-out fatigue

FMT, Fecal Microbiota Transplantation

Whitmore LC, Weems MN, Allen LH (2017) Cutting edge: Helicobacter pylori induces nuclear hypersegmentation and subtype differentiation of human neutrophils in vitro