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Regarding papaverine, a direct-acting vasodilator, when injected intraperitoneally in noise-exposed Wistar rats significantly decreases the apoptotic death of hair cells resulting in significantly smaller threshold shifts when compared to noise-exposed untreated animals (Kum et al., 2018)

This is especially so in singers, even though when done well, such surgery is extremely safe and voice restoring

The copy number variant of the HBD2 gene variant DFEB4 and circulating protein concentrations have been investigated in stroke patients (Tiszlavicz et al., 2012)