glutathione peroxidase upregulation degradation brain cholesterol

glutathione peroxidase upregulation degradation brain cholesterol 4: a new player in neurodegeneration? The role of glutathione peroxidase

Name: glutathione peroxidase upregulation degradation brain cholesterol 4: a new player in neurodegeneration? The role of glutathione peroxidase
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The role of glutathione peroxidase 4 in neuronal ferroptosis and its therapeutic potential in ischemic and hemorrhagic stroke ScienceDirect Glutathione peroxidase 4dependent glutathione highconsumption drives acquired platinum chemoresistance in lung cancerderived brain metastasis Liu 2021 Clinical and Translational Medicine Wiley Online Library Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease PMC The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity: Cell Reports Oxytosis Ferroptosis in Neurodegeneration: the Underlying Role of Master Regulator Glutathione Peroxidase 4 (GPX4) Molecular Neurobiology Springer Nature Link

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Echeverria, G

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Its multiple antioxidant, antiapoptotic, neuroprotective, anti-inflammatory and LOC DA release enhancer actions might be responsible for the protection in this disease with a complex, multifactorial pathomechanism