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Dosing, reconstitution, and injection instructions should come only from licensed health care sources.

206 In a placebo-controlled trial, 60 patients with stage 4 CKD who had been eating a low-protein diet for two months were assigned to add probiotic supplements providing 1 billion CFUs L

There was minimal muscle tenderness at injection site but no other side effects

You do need bioavailable active forms of vitamin B12 like methylcobalamin, adenosylcobalamin, or hydroxocobalamin