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To determine the effect of fasting on SIRT7, we cultured cancer cell lines under conditions of normal glucose concentration (mouse mammary tumor 4T1 cells, approximately 10 mM

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Mature DCs contain activated inflammatory TLRs and release high levels of inflammatory mediators, inducing the proliferation of Th1 and Th17 cells and targeting self-antigens, thereby directly or indirectly inhibiting chondrogenesis and promoting cartilage degeneration through the action of inflammatory MSCs (103, 104)