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Transcriptional regulators of the enzymes include the peroxisome proliferator-activated receptors (PPARs) and a transcription factor coactivator PGC-1a (and involve the retinoid X receptor), but the details of the process are tissue dependent

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But inflamed, infected, injured, or regenerating tissues are vulnerable to oxalate accumulation

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Tong et al., 2011

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Further, it may stimulate angiogenesis by interacting with cell surface ATP synthase enzymes [23, 26]

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