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If not treated, they can cause lasting damage

Rotate Injection Sites Repeated injections in the same area increase the likelihood of irritation and tissue sensitivity

Nature 502 , 559562 (2013)

Leucine zipper A common protein motif comprising predominantly of alpha helices

In 450 BC, the Greek physician Hippocrates used the amadou mushroom as an anti-inflammatory, while the first peoples of North America used puffball mushrooms (Calvatia genus) to heal wounds