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By methylating and removing nicotinamide, NNMT effectively drains NAD+ precursor availability, leading to reduced intracellular NAD+ levels

p 18 years of age) with CD followed at the University of Chicago between 2002 and 2015 [73]

It supports metabolism by helping convert food into energy

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Poor absorption of vitamin B 12 may be due to: alcoholism bowel disease, such as Crohn disease, celiac disease or a parasitic infection prior surgery that removed portions of the stomach or small intestine chronic use of medications for ulcers or heartburn such as antacids lack of a protein called "intrinsic factor" This protein is needed to absorb vitamin B 12 from the diet