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In vitro antioxidant studies demonstrated superior radical scavenging capacities for DPPH (87.11 2.54%), ABTS (93.72 2.87%), hydroxyl (86.45 1.62%), and superoxide anion (76.67 1.56%), significantly outperforming free rhCol III and B-LIPS

PMID: 26 ZhangHYuYWangJHanYRenTHuangYet al

Additionally, the gastrocnemius wet weight ratio in the SCI group was significantly lower than that in the GlyNAC+SCI group at 4 weeks ( P = 0.0006) and 8 weeks ( P = 0.0045) post-injury (Fig

Lactate induces the stemness potentials of detached breast cancer cells by promoting -KG-DNMT3B-mediated hypomethylation of SOX2 To clarify the metabolic-epigenetic mechanism of lactate-induced stemness potentials in detached breast cancer cells via fueling the TCA cycle, we next focused on -ketoglutarate (-KG), a vital signaling molecule regulating stemness gene expression and one of the top three significantly increased TCA cycle intermediates (oxaloacetate, succinate, -KG) in 13 C 3 -lactate treated AR cells (Fig