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All cell lines were cultured in suspension using RPMI-1640 medium (Gibco) supplemented 10% FBS (New Zerum), under the condition of 37 C and 5% CO 2

Apolipoproteins such as apolipoprotein E (apoE) have been shown to associate with neutral or near neutral lipid-containing lipid nanoparticles in the body, and are known to associate with receptors such as low-density lipoprotein receptors (LDLRs) found on the surface of hepatocytes

Sterile water works for single-use but provides no protection against contamination over multiple doses

Goal: Support telomere maintenance, melatonin regulation, and geroprotective effects over time [2]

Interruptions prevent the patterns from stabilizing, so REM gets lost first