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This drug can also be used for the acute management of ventricular arrhythmias occurring during cardiac manipulation such as cardiac surgery and life-threatening arrhythmias, particularly those that are ventricular in origin

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For details, see the updated Titanium Dioxide section of the Inactive Ingredients/Excipients article

Elevated ROS formation in the vessel wall is a key feature of cardiovascular disease and contributes to endothelial dysfunction, vascular inflammation, and cardiovascular remodeling (6)

[1] In 1911 Gunther described what is now known as the classic triad of abdominal pain, constipation (or diarrhea), and vomiting