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8 ways to treat arm pain after a vaccine Although a sore arm after COVID shots is temporary, there are a few things you can do at home to help treat a sore arm after your vaccine: Use a cold compress on the injection site Applying a cool compress or wet washcloth on the arm where you got the shot may help relieve pain and discomfort at the injection site

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However, complete symptom resolution often requires several weeks to months of consistent treatment

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