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10.1016/j.taap.2024.117072 15 ChoiS.LeeS.LeeK.ParkJ

Therapeutic indications

In this sense, the brain sends modulatory signals to the gut via vagus nerve and systemic circulation, perceived by the intestinal cells (including resident immune cells) and gut microbiota

Of note, the most elevated metabolites in NKX21 overexpressing versus control and (scramble) control versus NKX21 knockdown/knockout cells were related to ATP synthesis, nucleotide metabolism and redox homeostasis (Fig