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However, lung fibrosis was not observed in a different genetic mouse model where the DT expression is controlled by an inducible Cre recombinase knocked into the Sftpc locus (Barkauskas et al., Different studies in human and mouse models have attempted to provide biological insights into the association of TERT and TERC polymorphisms with pulmonary fibrosis

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Bussiere et al , 2020

Najczciej eksplorowany kierunek to postulowana aktywacja telomerazy enzymu odbudowujcego kocowe odcinki chromosomw (telomery) oraz normalizacja okoodobowego wydzielania melatoniny