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Binders often cause constipation which is typically well managed with magnesium and/or vitamin C

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A randomized, placebo-controlled trial in 559 elderly individuals with low serum levels of folate and vitamin B 12 and at increased risk of fracture evaluated the combined supplementation of very high doses of folic acid (5 mg/day) and vitamin B 12 (1.5 mg/day)

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Scientists have been drawn to this compound for its wide-ranging ability to target harmful changes in the body that ignite the cancer process