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Ann Neurol 1994;35:482-7

The high cost linked with these complex processes can pose commercial difficulties in peptide drug development

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Keywords: Drug induced liver injury (DILI), Endocrinology, Hepatotoxicity, Idiosyncratic hepatic injury, Risk factors INTRODUCTION A large number of drugs have deleterious effects on liver and drug-induced liver injury (DILI) is a major clinical problem

Given the risk of hemolytic crisis and related sequelae from various triggers in affected subjects in both malaria endemic and non-endemic regions, we believe that developing a pharmacological agent that corrects G6PD deficiency may benefit affected individuals