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Genotyping was assessed using two similar arrays, i.e., the UK BiLEVE array and UK Biobank Axiom array

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[00037] As used in the present disclosure, the term "effective amount" is interchangeable with "therapeutically effective amount" and means an amount or dose of a compound or composition effective in treating the particular disease, condition, or disorder disclosed herein, and thus "treating" includes producing a desired preventative, inhibitory, relieving, or ameliorative effect