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Siyuan Song, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Data availability In accordance with data sharing regulations imposed by the Western Norway Ethical Committee (REK-Vest) ( data may be shared by request to the corresponding author, subject to written permission from the REK-Vest

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As a result of this, a multistage carcinogenesis process starts, and cells with diseases may occur by the degradation of the balance between both lipophilic and enzymatic antioxidants that form the antioxidant capacity of skin and ROS