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30 Diagnosis Clinicians must rely on clinical experience, interpretation of symptoms, and evaluation of medical history in order to tentatively diagnose a patient as having Parkinson's disease

116,117 It is a homo-dimeric transmembrane protein whose extracellular domain can connect with the other same molecules of neighboring endothelial cells in the paracellular cleft, and the cytoplasmic domain can interact with the actin filaments via scaffolding proteins

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Plos Genet 16:e1008796 Laukoter S, Beattie R, Pauler FM et al (2020) Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex development