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38 In the absence of PTP1B, the decrease in ROS-mediated activation of JNK and p38 MAPK and the increase in IGFIR tyrosine phosphorylation might act in conjunction with the effects on the GSK3 /Src-Fyn axis, resulting in attenuated oxidative stress and increased cell survival in response to APAP

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J Microbiol Methods 140:1522

Stokes CR, Soothill JF, Turner MW