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Elevated uric acid is related to the no-/slow-reflow phenomenon in STEMI undergoing primary PCI

Proteins are very important signposts of cellular redox status and through their structure/function modulation, ROS can also influence gene expression profile by affecting intracellular signal transduction pathways

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Clinically, this resistance manifests in two distinct patterns, arising from both the progressive functional exhaustion of tumor-specific T cells and the dynamic equilibrium between immune attack and tumor evasion, which are continuously challenged within an immunosuppressive tumor microenvironment (TME) sculpted by immunoediting