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Intravenously administered ascorbate reaches a plasma concentration of approximately 885 mol/L, which is six times greater than the ascorbate plasma level that is equilibrated after orally administered ascorbate

(2026) Figures were prepared using Affinity Designer 2.6.0 (Serif) and GraphPad Prism v10.5.0 (GraphPad Software, San Diego, CA, USA)

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4d), indicating that part of the protective effect observed with NAC requires GSH synthesis

Replacing sodium phosphate buffer with HEPES buffer did not result in a notable change in enzyme activity, confirming that phosphate does not inhibit the activity of Cp1B (Supplementary Fig