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We have high hopes that this review can bring novel concepts and fresh perspectives for the further development of PD treatments since it will carefully update the present trial status and conduct an analysis of the therapeutic options [16]

J Exp Mar Biol Ecol 187:6380 Abele-Oeschger D, Oeschger R, Theede H (1994) Biochemical adaptations of Nereis diversicolor (Polychaeta) to temporarily increased hydrogen peroxide levels in intertidal sandflats

2017;6(8):e371

Together, these mitochondrial events encompassing cristae loss, membrane destabilization, m collapse, and aberrant fission converge to disrupt oxidative metabolism and promote the energetic failure that accompanies ferroptotic cell death