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With the ongoing accumulation of intracellular iron ions, a notable increase in the levels of iron cycling phase proteins, including DMT1 and TFR1, occur within both osteoblasts and osteoclasts (131, 132)

Prostaglandins Leukot Essent Fatty Acids 80, 918 (2009)

The effect of concomitant beta-blocker use on survival in patients with metastatic renal cell carcinoma treated with a vascular endothelial growth factor receptor inhibitors in the first line

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It is particularly important in acetaminophen overdoses where increasing GSH levels by supplementing the precursor N-acetylcysteine (NAC) is the treatment of choice to clear the toxic intermediate metabolite N-acetyl-p-benzoquinone imine (NAPQI) via conjugation [14]