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Long COVID and its management

Phloretin and phloridzin guard against cisplatin-induced nephrotoxicity in mice through inhibiting oxidative stress and inflammation

TGF- is a major fibrogenic cytokine, regulating the production, degradation and accumulation of the extracellular matrix in hepatic fibrosis

Homocysteine has been identified as a pathogenic feature of NAFLD in humans and alcoholic fatty liver disease in a rodent model

We also tested a non-CRC model, the osteosarcoma U2OS cell line, which is wild-type for APC, KRAS and p53, and confirmed a similar 5FU-driven change in mitochondrial mass and morphology (Extended Data Fig