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While numerous questions can be asked in the context of glutamine metabolism and TB pathogenesis, a solid first step could be investigating the impact of Mtb upon the metabolic profiles of the immune cells and using the knowledge to block glutamine metabolism mindfully and selectively

Hence, why would I expose my patient to the risks of an unknown compound that has never been tested rigorously in humans when I can get the same results with PRP which has been tested for orthopedic applications in dozens of randomized controlled trials in humans

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Also, in vitro studies indicate that the responsiveness of pro-B cells to IL-7 is compromised in aged individuals [355], and IL-7 release from stromal cells in the bone marrow also declines with age [356], leading to reduced pro B-cell proliferation