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Neuroscience 276 , 7286 (2014)

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Additionally, studies evaluating the role of ATs in human diseases rarely define which specific ROS are involved, their sources, how they reach their molecular targets, and which targets are affected, and why

From a clinical perspective, because of the questionable role of GSH-Px, any patient with hemolytic anemia and reduced GSH-Px activity should be extensively evaluated for other causes of hemolysis

Furthermore, in tubular cells stimulated with TGF-1, a decrease in GSH concentration and enhanced lipid peroxidation, which are characteristic changes of ferroptosis, were observed