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The CFs with GSTM1 knockdown exhibited enhanced ECM production even without TGF- stimulation, as indicated by upregulation of fibrotic markers at both mRNA and protein levels compared to the control group (Fig

Duclos-Bastias D

While moderate treatment typically results in non-permanent damage 16 , longer treatment times can induce, e.g ., apoptosis 17

Saldeen, P., & Saldeen, T

About one third of AIH patients present acutely with jaundice, severe fatigue, nausea, and abdominal pain, meeting the criteria of acute severe AIH, which is defined by jaundice and INR between 1.5 and 2 in absence of known pre-existing liver disease