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In addition, we found that pre-treatment with ISO reduced the loss of mitochondrial membrane potential, improved cell morphological damage, and inhibited apoptosis in H 2 O 2 -induced HaCaT cells

If the affinity of the DNA binding protein is specific to a known DNA binding site, it is sufficient to include that binding site and the sequence encoding the DNA binding protein in the genetic vaccine vector together with such other coding and regulatory sequences are required to effect gene therapy

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One of the mechanisms supporting this resistance is the interaction between FOXO4 and p53 within the nucleus