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However, this increase in BUN is also affected by other factors: the concomitant loss of HS at least in part explains the increase in BUN and fully explains the CLP-induced decrease in glomerular filtration rate (GFR) (98)

These data support that the presence of an amino acid residue with a branched aliphatic side chain, or a methionine, at position 585 of albumin is required for optimal FcRn binding