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Portilho et al

doi:10.1155/2021/5564824 Shishehgar F, Mirmiran P, Rahmati M, Tohidi M, Ramezani Tehrani F

Exon Publ

In summary, rational design of dosage forms for engineered live bacterial therapeutics must be tailored to both disease phenotype and administration route

Eliminating the ability of CspZ to bind FH exposes the FH-binding site and, therefore, may increase the ability of the epitopes close to/within this site to induce bactericidal antibodies