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doi: 10.1016/j.ejogrb.2016.08.026

Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view

While it is available as a licensed prescription medicine for confirmed carnitine deficiency, over-the-counter supplements occupy a very different regulatory space

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AD Actinomycin-D, ALC Acetyl-L-carnitine, BDR Blastocyst development rate, GSH Glutathione, HTF Human tubular fluid, H 2 O 2 Hydrogen peroxide, IVC in vitro embryo culture, IVF in vitro fertilization, IVM in vitro maturation, LC L-Carnitine, OS Oxidative stress, ROS Reactive oxygen species, TNF-tumor necrosis factor, ZP Zona pellucida During in vitro fertilization (IVF) procedures, embryo fragmentation due to apoptosis is a common occurrence that is well documented