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Fracchiolla D, Chang C, Hurley JH, Martens S A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy

Hit 3 was then selected for structure-activity relationship studies, leading to the identification of structural analogues that retained anti-DENV activity through the disruption of NS3-NS5 interaction

Arch Biochem Biophys 726:109231

Vitamin B12 injections are administered for various reasons, primarily to counteract deficiencies that cannot be resolved by dietary changes or oral supplements alone