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For example, decanoic acid (C10), a medium-chain fatty acid, enhances mitochondrial function and biogenesis via PPAR- activation and improves brain energy metabolism

NR4A1 is capable of directly interacting with metformin, influencing the localization of Liver Kinase B1 (LKB1), activating AMPK, and decreasing the generation of inflammatory signals and intracellular ROS

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Neurons innervating the striatum, including dopaminergic neurons from the SNcVTA regions, take up AA, which, in low-TH-expressing cells, the phenotype can switch to a dopaminergic one through TH synthesis

10.1016/j.jcis.2004.02.012