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*Correspondence: Xiao-Hong Sun, [email protected] This article was submitted to Parkinsons Disease and Aging-related Movement Disorders, a section of the journal Frontiers in Aging Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Administration of low concentrations of luteolin (15 M) resulted in enhanced cell viability, inhibition of lactate dehydrogenase (LDH) release, and a reduction in levels of IL-1, concomitantly modulating the expression of genes pertinent to PD: specifically, an elevation in Park2, a reduction in Lrrk2, and an enhancement of Nrf2 and Trx1 expression

The expected increase of m / z was only observed in the matrix-assisted laser desorption ionization (MALDI) spectra of the wild-type enzyme, in line with an S -glutathionylation at C13 (Extended Data Fig

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