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A young child's brain is especially dependent on receiving ample amounts of oxygen and energy for proper growth and development

Its interaction with the mitochondrial electron transport chain elicits the generation of ROS, which subsequently initiates the process of lipid peroxidation [26]

Mitochondrial GSTs are also known as kappa class GSTs and are soluble enzymes which bear structural similarities with cytosolic GSTs

Sonja Hochmeister, Medical University of Graz, Austria Updates Copyright 2023 Coutinho Costa, Arajo, Alves-Leon and Gomes

Gefitinib an EGFR tyrosine kinase inhibitors resistance, was approved for second-line treatment of advanced NSCLC in 2004 and first-line treatment of patients with EGFR mutations in 2010