glutathione trapping reactive metabolites

glutathione trapping reactive metabolites of drug produced by biomimetic metalloporphyrin catalysts - Lassila - 2015 - Rapid Communications in Mass Spectrometry Comparison of trapping profiles between

Name: glutathione trapping reactive metabolites of drug produced by biomimetic metalloporphyrin catalysts - Lassila - 2015 - Rapid Communications in Mass Spectrometry Comparison of trapping profiles between
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Comparison of trapping profiles between d peptides and glutathione in the identification of reactive metabolites ScienceDirect Toxicity of Glutathione Binding Metals: A Review of Targets and Mechanisms Glutathione Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Reactive Metabolite Factsheet Evotec Glutathione Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation PMC

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To determine how APR-246 depletes GSH, we applied mass spectrometry to show that 2-methylenequinuclidin-3-one (MQ), the active component of APR-246, reacts with GSH inside cancer cells (Fig