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A strong cytoskeleton network plays an integral role in the ability of the NP to withstand the compressive mechanical load and stress

Similar to the transcriptomic changes observed in the hypothalamus, we found that the conjugate prompted transcriptional patterns enriched for functional terms associated with synaptic transmission, including postsynaptic specialization and neuron-to-neuron synapse in the brainstem (Extended Data Fig

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doi:10.1016/j.jep.2006.03.042 16

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension