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For RA and T1D, given limited evidence from small-sample clinical studies or preclinical models, these interventions are currently in the exploratory stage and not recommended to replace conventional immunomodulators

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However, persistent and aggravated abnormal signals of the sCC in multiparameter MRI, including crescent-shaped hyperintensity in T 2 WI and hyperintensity in phase imaging, and damaged structures, particularly in the FA map of DTI, were observed in the 4w group (Fig