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De Sousa C, Leung NW, Chalmers RA, et al

| 2022 | Molecular Biology Reports, particularly by restoring NAD to more youthful levels

-ketoglutarate dehydrogenase and pyruvate dehydrogenase are involved in redox reactions to generate NADH and FADH 2 in the tricarboxylic acid (TCA) cycle [95], then in the electron transport chain (ETC), complexes I, II, and III perform redox reactions to generate ATP [18]