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Further, another inflammatory pathway marker transcription factor, nuclear factor kappa B (NF-B) activity has been shown to be increased in the brains of AD patients (Hong, Mast cells are present adjacent to the neurons and glial cells in thalamus, hypothalamus, and leptomeninges and activate them by cell-to-cell contacts as well as by releasing inflammatory and neurotoxic mediators (Theoharides et al., 2013)

NAC is widely used because it can help restore intracellular cysteine levels and support glutathione production

However, N-propylamide and N-butylamide were also active, but their potency was low

The Annals of the New York Academy of Science

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