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HIF-1 plays a protective role in maintaining the dynamic balance of the articular cartilage matrix, whereas HIF-2 negatively decomposes the articular cartilage matrix

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Notwithstanding, PF media contain no albumin or other protein, which could reduce contamination risk but often result in slower growth and lower viability (Butler, 2015)

If any reaction occurs, stop using it immediately

Gibco, 16000044), 1% penicillin and streptomycin (Biowest, L0022-100), and 1% non-essential amino acids (Gibco, 11140-050)