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for improved stability, targeting, etc.) and should be delivered to cells -which express the polynucleotides of the invention in vivo

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DSIP is under active research for potential application in: Individuals with insomnia or light, fragmented sleep Those with chronic stress or HPA axis dysfunction Athletes and biohackers seeking enhanced recovery People working night shifts or experiencing circadian misalignment Adults with low growth hormone output or reduced sleep efficiency Patients with PTSD or trauma-related sleep disruption (research ongoing) DSIP is not FDA-approved for any medical condition and should only be used in research settings under supervision

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During radiotherapy, depleting GSH improves treatment efficacy by impairing the cells ability to neutralize ROS [85]