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In Italy, the incidence of TB is relatively low compared to global rates, with around 4.1 cases per 100,000 people in 2022, with 2,439 new cases

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102 In vitro treatment with 1-h H 2 O 2 demonstrated that the catalytic activity of POLG was reduced to 50% of the original level with significantly lower DNA binding efficiency

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Their phospholipid structure gets more chylomicrons in enterocytes and thus encourages more production

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As is known, LPO is catalyzed by intracellular iron or lipoxygenases and cytochrome P450 oxidoreductase, leading to its deposition in the biomembrane to increase membrane permeability and hence initiate the process of cell death

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