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Techniques to improve measurement of individual exposure suitable for use in epidemiological studies have been developed, and do provide a better opportunity to accurately relate dose to effects

14 , 538.e1538.e7 (2018)

Several RNAi drugs, including aptamers like pegaptanib targeting protein targets, and micro interfering RNAs like givosiran and patisiran, as well as antisense oligonucleotides like golodirsen and inotersen that interfere directly with RNA targets, have received FDA approval for medical use (Yu et al., 2020)

The half-unit measurements at 20mg/mL create a practical challenge

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